• Associate Professor
School of Pharmacy - Pharmaceutical Chemistry
Simons Biosciences Research Laboratories, Room 256
University of Kansas
2093 Constant Avenue
Lawrence, KS 66047


  • Postdoctoral, Department of Biochemistry, Stanford University School of Medicine, Stanford, CA (1998 - 2001)
  • Postdoctoral, Victorian College of Pharmacy (now Monash University), Melbourne, Austrailia
  • Ph.D. (w/honors), Pharmaceutical Chemistry, University of Kansas, Lawrence, KS (1998)
  • B.S., Pharmacy, Duquesne University, Pittsburgh, PA (1993)


Professional Experience

  • Associate Professor, University of Kansas, Department of Pharmaceutical Chemistry (2004 - present)
  • University of North Carolina at Chapel Hill, Division of Drug Delivery (2001)

Research Overview

The Krise laboratory seeks to understand how drugs distribute and localize within human cells and how this influences their therapeutic activity and pharmacokinetic distribution properties. Much of our recent studies have focused on the intracellular distribution of amine-containing drugs and their propensity to become highly concentrated in acidic intracellular compartments such as lysosomes according to an ion trapping-type mechanism.

Research Interests

  • Drug delivery
  • Pharmacokinetics
  • Prodrugs
  • Intracellular

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Our research projects ranging from traditional pharmaceutics to biotechnology. 

Learn more here.