Lab samples in glass tubes and bottles

David Volkin Research

David Volkin
David Volkin Research
University of Kansas
Multidisciplinary Research Building Room (MRB), Room 304
2030 Becker Drive
Lawrence, KS 66047

Research Overview

Lack of stability often limits the use of biopharmaceuticals and vaccines (e.g., proteins, DNA/RNA, virus-like-particles, and viruses) as human medicines.  Loss of potency can occur during manufacturing, storage, or administration.  Our research objective is to understand the changes in physicochemical properties that accompany the loss of biological activity, and to develop new analytical techniques to monitor these changes at the molecular level.  A detailed understanding of the causes and molecular mechanisms of instability will guide the design of more potent and stable biopharmaceutical and vaccine dosage forms  As co-founder of the Vaccine Analytics and Formulation Center at The University of Kansas, our group collaborates extensively with partners (non-profits, small/large biopharma/vaccine companies, and academia) on analytical characterization and formulation development projects to facilitate novel candidates entering clinical trials with an emphasis on new candidates for use in the developing world.. 

David Volkin Research